Speeding up the toxicology processes

~ How ToxHQ can help reduce lead times ~

For any product manufacturer or developer in nicotine, pharmaceuticals or medicinal cannabis, it is essential that you have robust, reliable toxicological data. Toxicology assessments can be time consuming, but it is an area where product developers can reduce lead time, enabling them to bring products to market quicker. Here, Dean Hatt, Senior Toxicology Consultant and Toxicology Manager, explains how ToxHQ can aid the process.

ToxHQ is a chemical repository that stores the properties of over 400 chemicals, including hazard assessments, health-based guidance values and in vivo/in vitro toxicological information. With this repository, Broughton can create toxicology profiles at the press of a button using existing data which is constantly being reviewed and updated. For any customer looking to bring a particular new product to market, a specific or bespoke toxicology report can be auto generated within this database, instantly providing savings by reducing lead times.

By storing all of the toxicology data in one place, ToxHQ can utilise key information to perform risk assessments on formulations, products and datasets.

By utilising data from the repository or provided as ‘blinded’ data by a customer, these risk assessments are created on screen as the formulation is built, allowing a real time opportunity to make changes to a product or formulation. In addition, the confidential nature of ToxHQ means a secure area is created for customers that even Broughton may not have access to – allowing risk assessments of materials and liquids to have strict access control.

While other contract research organisations have databases that provide access to clients, this may not provide the same level of confidentiality that sits within ToxHQ.

Though originally designed for customers involved in e-cigarette product development, this platform caters for all new generation nicotine products as well as products and formulations in both pharmaceutical and medicinal cannabis sectors too. As long as the chemical information exists or is provided the platform can be used in a multitude of different ways.

Product developers at any stage of the process can use ToxHQ, whether that’s early testing at the prototype phase to assess what should and shouldn’t be included in the final product, or final testing to generate a toxicology profile or risk assessment for a product ahead of regulatory submission.

To find more about Broughton’s toxicology services and what they entail, visit Broughton’s toxicology service page.